Coxiella (Philip, 1943) Philip, 1948
- Dataset
- English Wikipedia - Species Pages
- Rank
- GENUS
Classification
- genus
- Coxiella
Abstract
Coxiella refers to a genus of Gram-negative bacteria in the family Coxiellaceae. It is named after Herald Rea Cox (1907–1986), an American bacteriologist. It is one of the Gammaproteobacteria. Coxiella burnetii is the only member of this genus. It is an intracellular parasite and it survives within the phagolysosomes of its host. It causes Q fever.
Molecular Signatures
Seven conserved signature indels (CSIs) were identified through genomic analyses as exclusively shared by C. burnetii and other unnamed Coxiella-related species in the proteins glutamine-hydrolyzing GMP synthase, type I methionyl aminopeptidase, ribonucleoside-diphosphate reductase subunit alpha, translation initiation factor IF-3, phosphomannomutase-phosphoglucomutase, LPS export ABC transporter ATP-binding protein, and NADH-quinone oxidoreductase subunit G. These CSIs serves to reliably demarcate the genus from other Legionellales species in molecular terms. Additionally, three CSIs were identified as uniquely shared between the genus Coxiella, and two other genera belonging to the family Coxiellaceae, Diplorickettsia and Rickettsiella. The absence of Aquicella species (the remaining genus within the family Coxiellaceae) from the shared CSIs suggests that the genera Coxiella, Diplorickettsia and Rickettsiella share a common ancestor exclusive of Aquicella.